The role of Bacillus subtilis in laying hens breeding

The role of Bacillus subtilis in laying hens breeding枯草芽孢杆菌在蛋鸡养殖中的作用

In laying hens, Bacillus subtilis is the most common probiotic that can produce various enzymes, antimicrobial peptides, and other substances. Bacillus subtilis has multiple synergistic effects when used together with other probiotics, traditional Chinese medicine, and plant extracts.在蛋鸡中，枯草芽孢杆菌是最常见的益生菌，可以产生各种酶、抗菌肽和其他物质。枯草芽孢杆菌与其他益生菌、中药和植物提取物一起使用时具有多重协同作用。

The role of Bacillus subtilis in laying hens breeding:枯草芽孢杆菌在蛋鸡养殖中的作用:

1. Adjust the balance of gut microbiota in laying hens. Bacillus subtilis is an anaerobic bacterium that can consume oxygen in the intestines of laying hens, promote the proliferation of dominant gut microbiota such as lactic acid bacteria and bifidobacteria, reduce the number of pathogenic bacteria, and improve gut microbiota.1. 调节蛋鸡肠道菌群平衡。枯草芽孢杆菌是一种厌氧菌，能消耗蛋鸡肠道内的氧气，促进乳酸菌、双歧杆菌等优势肠道菌群的增殖，减少致病菌数量，改善肠道菌群。

2. Antibacterial substances produced by Bacillus subtilis, such as bacteriocins and lipid antibiotics, can compete with pathogens for adhesion sites, reducing their invasion of cells. The metabolites of Bacillus subtilis can stimulate the production of immunoglobulins in laying hens, enhancing their immune system.2. 枯草芽孢杆菌产生的抗菌物质，如细菌素和脂类抗生素，可以与病原体竞争粘附位点，减少病原体对细胞的侵袭。枯草芽孢杆菌的代谢产物能刺激蛋鸡免疫球蛋白的产生，增强蛋鸡的免疫系统。

In the actual production process, Bacillus subtilis is usually used together with other feed additives such as lactic acid bacteria, yeast, plant extracts, enzyme preparations, Chinese herbal medicine, fermentation products, etc., and has various synergistic effects:在实际生产过程中，枯草芽孢杆菌通常与乳酸菌、酵母菌、植物提取物、酶制剂、中草药、发酵产物等其他饲料添加剂一起使用，并具有多种协同作用:

1. The microecological preparation composed of Bacillus subtilis and lactic acid bacteria, yeast, etc. has a positive effect on improving egg quality, enhancing antioxidant capacity and immunity, and reducing Salmonella infection.1. 由枯草芽孢杆菌与乳酸菌、酵母菌等组成的微生态制剂对改善鸡蛋品质、增强抗氧化能力和免疫力、减少沙门氏菌感染等具有积极作用。

2. Bacillus subtilis has a synergistic effect with various feed additives.2. 枯草芽孢杆菌与多种饲料添加剂具有协同作用。

(1) Bacillus subtilis and silk orchid extracts have a positive effect on promoting the intestinal health of laying hens and reducing ammonia pollution in chicken coops.(1)枯草芽孢杆菌和丝兰提取物对促进蛋鸡肠道健康和减少鸡舍氨污染具有积极作用。

(2) Bacillus subtilis and Atractylodes macrocephala polysaccharides have a synergistic effect on the growth performance and serum immune indicators of laying hens during the breeding period.(2)枯草芽孢杆菌和苍术多糖对蛋鸡育苗期的生长性能和血清免疫指标具有协同效应。

(3) Bacillus subtilis and Astragalus polysaccharides have a positive effect on improving the growth performance of chicks, significantly increasing immune organ development, antibody concentration, and serum lysozyme content.(3)枯草芽孢杆菌和黄芪多糖对提高雏鸡生长性能有积极作用，显著提高免疫器官发育、抗体浓度和血清溶菌酶含量。

(4) The combination of Bacillus subtilis and alfalfa polysaccharides can improve the production performance and egg quality of laying hens, reduce the number of Escherichia coli in feces, increase the number of bifidobacteria in the intestine, and improve immune performance.(4)枯草芽孢杆菌与苜蓿多糖联合使用可提高蛋鸡的生产性能和蛋品质，降低粪便中大肠杆菌数量，增加肠道中双歧杆菌数量，提高免疫性能。

(5) The combination of Bacillus subtilis and traditional Chinese herbal formulas (such as astragalus, hawthorn, and tangerine peel) can increase egg production rate and reduce feed to egg ratio in laying hens, as well as reduce the rate of unqualified eggs, with a synergistic effect.(5)枯草芽孢杆菌与中药配方(如黄芪、山楂、陈皮)配伍可提高蛋鸡产蛋率，降低料蛋比，降低不合格蛋率，具有协同效应。

(6) Bacillus subtilis used together with bile acid can reduce the incidence rate of hepatitis in laying hens and prolong the laying period.(6)枯草芽孢杆菌与胆汁酸配合使用可降低蛋鸡肝炎发病率，延长产蛋期。

(7) The use of Bacillus subtilis in combination with organic rare earth - rare earth - thiofenone can reduce the inflammatory response of the fallopian tubes in laying hens, increase egg production rate, improve egg quality and eggshell quality, and egg weight.(7)枯草芽孢杆菌与有机稀土-稀土-硫芬酮联合使用可降低蛋鸡输卵管炎症反应，提高产蛋率，改善蛋品质和蛋壳品质，改善蛋重。

(8) The combination of Bacillus subtilis and phytase can improve the utilization efficiency of nitrogen and phosphorus in feed for laying hens.(8)枯草芽孢杆菌与植酸酶配合使用可提高蛋鸡对饲料中氮、磷的利用效率。

Two key points for Bacillus subtilis to improve the efficiency of laying hens:枯草芽孢杆菌提高蛋鸡生产效率的两个关键点:

1. Eggshell quality is an important indicator for measuring egg quality and is influenced by diseases, nutritional status, heat stress, age, and other factors. Bacillus subtilis can improve egg quality, enhance the production performance of laying hens, increase egg production rate, and reduce feed to egg ratio.1. 蛋壳品质是衡量鸡蛋品质的重要指标，受疾病、营养状况、热应激、年龄等因素的影响。枯草芽孢杆菌能改善蛋品质，提高蛋鸡生产性能，提高产蛋率，降低料蛋比。

2. The balance of gut microbiota is an important indicator affecting the health status of laying hens. Bacillus subtilis can effectively inhibit the growth of pathogenic bacteria in the intestines of laying hens, increase the proliferation of various probiotics in the intestines, and reduce diseases.2. 肠道菌群平衡是影响蛋鸡健康状况的重要指标。枯草芽孢杆菌能有效抑制蛋鸡肠道内致病菌的生长，增加肠道内各种益生菌的增殖，减少疾病。