What are the benefits of adding Bacillus subtilis to feed

Adding Bacillus subtilis to feed has many benefits, including:

1、 Improvement of animal intestinal health

Regulating the balance of gut microbiota

      After entering the animal intestine, Bacillus subtilis can rapidly reproduce. It can competitively inhibit the growth of harmful bacteria such as Escherichia coli, Salmonella, etc. For example, Bacillus subtilis can form a biological protective film on the surface of the intestinal mucosa, preventing harmful bacteria from adhering and colonizing on the intestinal mucosa.

      At the same time, it can also promote the proliferation of beneficial bacteria such as bifidobacteria, lactobacilli, etc. By secreting substances that promote the growth of beneficial bacteria, such as short chain fatty acids, a favorable living environment is created for beneficial bacteria, thereby optimizing the structure of the gut microbiota.

Enhance intestinal barrier function

      It can stimulate the growth and development of intestinal mucosal cells, promote the growth of intestinal villi, and increase the absorption surface area of the intestine. For example, adding Bacillus subtilis to piglet feed increases the length and density of intestinal villi, which helps with nutrient absorption.

      Moreover, it can enhance the expression of tight junction proteins in the intestine, making the intestinal mucosal barrier tighter, reducing the penetration of harmful substances (such as endotoxins, pathogens, etc.), and lowering the risk of intestinal inflammatory reactions.

2、 Improvement of animal digestive function

Generate digestive enzymes

      Bacillus subtilis can secrete various digestive enzymes, such as amylase, protease, lipase, etc. These enzymes can help animals better break down and digest nutrients in their feed. For example, amylase can break down starch into small molecule sugars such as maltose, protease can break down proteins into amino acids and small peptides, and lipase can help hydrolyze fats, thereby improving feed utilization.

Improve the absorption of nutrients

      Due to its improved intestinal environment, it promotes the absorption of nutrients by the intestine. On the one hand, by regulating the balance of gut microbiota, it reduces the competition and consumption of nutrients by harmful bacteria; On the other hand, enhanced intestinal barrier function and digestive function also enable nutrients to be more effectively absorbed into the bloodstream, providing sufficient nutrition for animal growth and production.

3、 Enhancement of animal immunity

Activate the immune system

      Bacillus subtilis can stimulate the development and function of intestinal associated lymphoid tissues in animals. For example, it can induce immune cells in the intestine (such as macrophages, lymphocytes, etc.) to produce immunoglobulin, enhancing the humoral immunity of animals.

      At the same time, it can also activate the innate immune response of the intestinal mucosa, enhance the non-specific immune defense ability of animals by recognizing and clearing pathogen related molecular patterns.

Improvement of disease resistance ability

      Enhanced immunity enhances animals' resistance to pathogens. When faced with disease challenges, such as infection with pathogens such as viruses or bacteria, animals added with Bacillus subtilis often exhibit milder symptoms and higher survival rates. For example, in aquaculture, adding Bacillus subtilis can reduce the occurrence of diseases caused by pathogenic bacteria such as Vibrio in aquatic animals.

4、 Improvement of feed quality

Improve feed stability

      Bacillus subtilis can inhibit the growth of harmful microorganisms such as mold during feed storage. It reduces the risk of feed mold and spoilage and extends the shelf life of feed by competing for nutrients and living space, as well as secreting some antifungal substances.

Improve feed palatability

      Some Bacillus subtilis strains can produce aroma compounds such as esters, alcohols, and other volatile organic compounds during fermentation, which give the feed a better odor and taste, thereby increasing animal feed intake.