The addition of Bacillus subtilis can reduce the probability of animals getting

      The addition of Bacillus subtilis can indeed reduce the probability of animals getting sick to a certain extent. The following is a detailed explanation of the reasons:
Improving the gut microbiota environment

Competitive dominance:

      There are various microorganisms in the intestines of animals, including probiotics, harmful bacteria, and many other microbial communities that together form the gut microbiota. After entering the intestinal tract of animals, Bacillus subtilis can quickly colonize on the surface of intestinal mucosa and other parts, occupying the adhesion sites of intestinal epithelial cells. This makes it difficult for harmful bacteria that could have caused diseases, such as pathogenic Escherichia coli and Salmonella, to find suitable locations to attach and reproduce, thereby limiting the growth of harmful bacteria in space, reducing their chances of causing damage to the intestine, and lowering the risk of intestinal infectious diseases in animals.

      For example, in poultry farming, the addition of Bacillus subtilis can occupy sites in the intestine, leading to a significant reduction in the number of pathogenic Escherichia coli and a decrease in the occurrence of intestinal diseases such as diarrhea in poultry.

Regulating the balance of gut microbiota:

      Bacillus subtilis can secrete various beneficial metabolites, such as bacteriocins and short chain fatty acids. Bacteriocins can inhibit the growth of some harmful bacteria in the intestine, have a killing effect on them, and maintain the population of harmful bacteria at a low level; Short chain fatty acids can provide a suitable acidic environment and nutrients for the growth of beneficial bacteria in the gut, such as bifidobacteria, lactobacilli, etc., promoting the proliferation of beneficial bacteria and improving the structure of the entire gut microbiota, allowing beneficial bacteria to occupy a dominant position in the gut microbiota, enhancing the barrier function and immune regulation ability of the gut, and strengthening animal resistance to diseases.

      Taking piglet farming as an example, after adding Bacillus subtilis, the number of lactobacilli in the intestine increased, the number of harmful bacteria decreased, the piglet intestine became healthier, and the frequency of intestinal inflammation and other diseases significantly decreased.

Enhance the immune function of animal bodies

Stimulating the development of immune organs:

      Bacillus subtilis can act on the immune organs of animals, such as the spleen and thymus, promoting the proliferation and differentiation of immune cells in these organs, enabling them to better perform their immune functions. The spleen is an important immune organ in animals, responsible for filtering blood, clearing pathogens, and generating immune responses; The thymus is the site where T lymphocytes develop and mature. Bacillus subtilis can stimulate the cell growth and functional perfection of these immune organs, making the animal's immune system more robust.

      In mouse experiments, it was found that long-term feeding with feed supplemented with Bacillus subtilis increased the spleen index (the ratio of spleen weight to body weight, which can reflect the development of the spleen to a certain extent) and thymus index of mice, indicating better development of their immune organs and enhanced ability to cope with pathogen invasion.

Activate immune cell activity:

      It can activate immune cells such as macrophages and lymphocytes in animals. Macrophages have functions such as phagocytosis of pathogens, clearance of foreign objects in the body, and presentation of antigens. Activated macrophages have greatly enhanced phagocytic ability and can more efficiently remove invading bacteria, viruses, and other pathogens from animal bodies; Lymphocytes can participate in specific immune responses, such as B lymphocytes producing antibodies to neutralize pathogens, and T lymphocytes directly killing cells infected by pathogens. When these immune cells are activated, the entire body's immune defense network becomes more stringent, and the likelihood of animals falling ill decreases accordingly.

      For example, in aquaculture, feeding fish with feed containing Bacillus subtilis enhances the activity of macrophages in the fish's body, significantly improves resistance to some common bacterial fish diseases, and significantly reduces the number of diseased fish.

Improve the digestion and utilization efficiency of nutrients

Generate digestive enzymes:

      Bacillus subtilis can secrete various digestive enzymes on its own, such as amylase, protease, lipase, etc. In the digestive tract of animals, amylase can help break down starch like substances and convert them into sugars that are easier for animals to absorb; Proteases can hydrolyze proteins into small molecule peptides and amino acids, which are convenient for animal intestinal absorption and utilization; Lipase is responsible for breaking down fat into absorbable components such as fatty acids. When animals digest and absorb nutrients in their food more fully, their physical fitness becomes stronger, their growth and development are better, and their ability to resist diseases is correspondingly enhanced.

      For example, in pig farming, the addition of Bacillus subtilis increases the activity of amylase and protease in the pig intestine, improves the digestion rate of nutrients in the feed, and makes pigs grow more robust. The incidence of diseases is relatively reduced, especially the phenomenon of diseases caused by low immunity due to nutritional deficiency has been improved.

Improving intestinal physical condition:

      It can promote the growth and development of intestinal villi, which are small finger like protrusions on the surface of the intestinal mucosa. The larger the surface area, the more conducive it is to the absorption of nutrients. Bacillus subtilis makes the intestinal villi longer and denser, increasing the absorption area of the intestine and allowing nutrients to be better taken up by the animal body, ensuring that animals receive sufficient nutrients to maintain normal physiological and immune functions, and reducing the risk of illness caused by malnutrition.

      In poultry farming, the addition of Bacillus subtilis resulted in better morphology of intestinal villi, improved absorption efficiency of feed nutrients, and reduced susceptibility to diseases during growth.

      However, the addition effect of Bacillus subtilis is also affected by various factors, such as the dosage added, the activity of the strain, the type of animal, and the breeding environment. Only through reasonable use can it better play its role in reducing the probability of animal diseases.