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Research on the Application of Yeast Cell Wall

0 Author 2024-09-12 10:29:00

Product Overview 

This product is made from fresh Saccharomyces cerevisiae yeast, which is obtained through autolysis, high-efficiency enzymolysis, wall-breaking, centrifugation, concentration, drying and other processes. It is rich in β-glucan and MOS and other bioactive ingredients, which can enhance immunity, prevent disease and promote growth, relieve stress, adsorb toxins and supplement nutrition. It is widely used in pig, poultry, ruminant and aquaculture industry, which can help the efficient and sustainable development of aquaculture industry. This product is a green additive, the finished product is light yellow to yellow-brown powder, no odor.

Product Advantages 

  1. Rich in yeast β-1,3/1,6-D glucan and mannan oligosaccharide
  2. Natural immune enhancer, no residue, no toxic side effects.
  3. Good stability, can adapt to granulation, puffing and other processing conditions.
  4. Advanced separation and extraction process, stable product quality

Product Specification 

Crude protein≤35% Moisture≤10% Crude ash≤10% Dextran≥18% Glycans≥18%

Crude protein≤40% Moisture≤10% Crude ash≤10% Dextran≥20% Glucan≥20%

Product efficacy 

  1. Adsorb pathogenic bacteria and various mycotoxins, such as Salmonella, E. coli, etc., the adsorption rate of more than 90%.
  2. Regulate immunity, enhance specific and non-specific immunity, reduce mortality rate 
  3. Relieve stress, improve survival rate
  4. Improve production performance

Product Mechanism 

 

  1. Adsorption and discharge of pathogenic bacteria

The mannan oligosaccharide in the yeast cell wall can competitively combine with pathogenic bacteria, impede the adhesion of pathogenic bacteria on the intestinal wall, and adsorb and discharge from the body.

 

2. Activate the immune system

The β-glucan in the yeast cell wall acts on the receptors on the surface of immune cells and activates the body to produce non-specific and specific immune response through a series of pathways.

 

(Godfrey,2009)

 

3. The special spatial structure provides more toxin binding sites and firmly adsorbs a variety of mycotoxins through intermolecular forces such as hydrogen bonding and van der Waals forces, preventing the toxins from being absorbed by the intestinal tract.

 

 

 

(A. Yiannikouris, 2006)

Related Applied Research 

Aquaculture 

Test animals 实验动物

Experimental details 实验的细节

Results 结果

Authors

Carassius auratus gibelio

Inoculation with inactivated columnar fibrophilic bacterial vaccine and feeding diets containing yeast cell walls

1. Elevated agglutinating antibody potency in serum

2. Phagocytosis percentage and phagocytic index activity increased significantly.

Chen Changfu et al. 2004

   Anguilla japonica

Feeding diets containing yeast cell walls饲喂含有酵母细胞壁的饲料

1. Enhancement of lysozyme activity

2. Effectively enhance non-specific immune function

Chen Changfu et al. 2004

BoogieFish

Feeding diets containing yeast cell walls饲喂含有酵母细胞壁的饲料

Immunization indices are up

Zhang, H. et al. 2011

Litopenaeus vannamei

Injection of β-glucan into South American white shrimp (Litopenaeus vannamei)

1. ACP and ALP activities in the hepatopancreas significantly increased immunopolysaccharide can activate the immune system of the South American white shrimp, Litopenaeus vannamei

Chen Changfu et al. 2004

Addition of β-glucan-containing preparations to feeds

Significantly increase shrimp weight gain, survival rate, significantly reduce feed coefficient

Liu, Donghui, 2002

 

 

Poultry 

Test animals 实验动物

Experimental details 实验的细节

Results 结果

Authors

pullet 小母鸡

Feeding diets containing yeast cell walls饲喂含有酵母细胞壁的饲料

1. Alleviate the suppression of immune function of broiler chickens by cyclosporin A1. 缓解环孢素A对肉鸡免疫功能的抑制作用

Binglin Liao et al. 2009刘炳林等人,2009年

Laying Chickens 将鸡

Feeding diets containing yeast cell walls饲喂含有酵母细胞壁的饲料

1. Improve the growth performance of laying hens1. 提高蛋鸡的生长性能

Wei Hengjie et al. 2010魏恒杰等人,2010

Broiler 

Feeding diets containing yeast cell walls饲喂含有酵母细胞壁的饲料

1. Increased serum globulin levels in chickens1. 鸡血清球蛋白水平增高

2. Increase in serum Newcastle disease antibody level.2. 血清新城疫抗体水平升高。

3. 3% reduction in mortality rate of broilers compared to the control group.3. 与对照组相比,肉鸡死亡率降低3%。

Li Chunsong et al. 2012李春松等人,2012年

Broiler Duck 烤肉鸭

Feeding diets containing yeast cell walls饲喂含有酵母细胞壁的饲料

1. Improve the digestibility, production performance and slaughtering performance of Cherry Valley ducks1. 提高樱桃谷肉鸭的消化率、生产性能和屠宰性能

Chen Hong et al. 2012陈红等,2012

 

 

Ruminants 

Test animals 实验动物

Experimental details 实验的细节

Results 结果

Authors

Calves

Oral yeast cell wall preparations

1. Increase the conversion rate of immature T and B lymphocytes in newborn calves.

2. Promote the secretion of antibodies by lymphocytes

Shan Puchuang et al. 2003

Calves

Feeding yeast cell wall containing feeds

1. Enhance calf immunity, reduce calf diarrhea, improve apparent digestibility of nutrients, and improve growth performance

Wei Hengjie et al, 2019

 Fattening Cattle       

Feeding yeast cell wall containing feeds

1. Improve the richness of intestinal bacterial community of fattening cattle, which is conducive to optimizing the intestinal microecological environment.

 

Wang Yan et al, 2024

Beach Sheep

Feeding yeast cell wall containing feeds

1. Improve the growth performance, immune function and antioxidant performance of beach goats

Ma Jifeng et al, 2021

 

Packing 

25kg/bag 

Loading Capacity 

Without pallet:20T/20FCL ; With pallet:16T/20FCL.

Shelf life 

12 months.

Scope of use 

1)Feed producers: it can be used in the addition of livestock and poultry, pet full-price feed, feed additives and premix.

2)Aquaculture, aquatic feed producers: can be used for aquatic fish, river crab, river shrimp fry with feed.

Dosage 

 

 

Category 

Proposed dosage (kg/T) 

Expected Effects

pig 

piglet 

1.5-2

Improve immunity system, decrease intestinal injury, relieve stress reaction and increase feed intake

Middle and big size pig

1-2

Improve resistance to disease, decrease the occurrence rate of intestinal disease, effectively absorb mycotoxin

Breeding pig2

Strengthen immune system, decrease the harm to breeding capacity caused by mould

Pregnant sow 

0.5-1.5

Increase antibody level, decrease the harm to breeding capacity caused by mould, prevent constipation

ruminant

foal

1.5-2.5

Good for growth of microorganism in rumen, and increase feed efficiency

dairy cow 

1-2

Improve immunity, prevent heat shock, extend milk production peak, improve milk quality

aquaculture 

normal 1-2, 

anti-stress 1.5-2.5, culture seedlings  1-2g/m3

Promote the growth of immune organs, increase the number of lymphocyte, lower down the death rate, improve water quality

Transportation of live animal 30-60g/m3

Decrease the harm of stress reaction to aquatic animals due to high temperature and poor oxygen during the transportation of live animals

poultry 

Breeding poultry 1-2

Decrease the adverse impact to feed quality

Meat poultry 

0.5-1.5

Avoid the harm caused by pathogenic bacteria, release the impact of stress reaction (due to high temperature, no water, no electricity ), obvious effect in weight increase

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