Application fields and scientific evidence of feed grade brewing yeast

      As a globally recognized functional feed ingredient, feed grade brewing yeast (Saccharomyces cerevisiae) has demonstrated multidimensional application value in livestock and aquaculture due to its unique nutritional composition (crude protein ≥ 45%, essential amino acid balance) and bioactive components (β - glucan ≥ 20%, oligosaccharides ≥ 8%). Based on international authoritative journal data and industry standards, the following systematically analyzes its core application scenarios:

1、 Pig farming: a full cycle solution from weaning stress to fattening and increasing efficiency

1. Optimization of intestinal health in weaned piglets

      In the 2021 Animal Feed Science and Technology study conducted by the European Union, the addition of 0.5% wall breaking brewing yeast (β - glucan 30%) to the diet reduced the diarrhea rate of weaned piglets by 28% (control group diarrhea rate 18.7% vs treatment group 13.5%), increased the ratio of intestinal villus height/crypt depth (V/C) by 19%, and significantly improved intestinal absorption function. The experiment conducted by the University of Minnesota in the United States showed that adding 1% brewing yeast culture can increase the average daily weight gain (ADG) of piglets by 12.3% (P<0.05), improve feed conversion rate (FCR) by 9.2%, and increase serum immunoglobulin IgG content by 22%.
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2. Improvement of growth performance of fattening pigs

      According to the 2022 data from the Journal of Applied Microbiology, replacing 5% soybean meal with brewing yeast (crude protein 52%) in a corn soybean meal diet can increase the daily weight gain of fattening pigs by 15.6%, reduce backfat thickness by 8.3%, and increase essential amino acid content in muscles by 11%. The organic selenium contained in it (0.3-0.5mg/kg) can increase the selenium content in pork to 0.35 μ g/g, which meets the EU certification standard for "selenium rich foods" (EC No 432/2012).
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2、 Ruminant animals: rumen fermentation regulation and sustainable aquaculture

1. Enhancement of lactation performance in dairy cows

      A 2020 experiment conducted by the University of Guelph in Canada showed that adding 200g/head/day of brewing yeast culture (viable cell count ≥ 1 × 10 ⁹ CFU/g) to the diet of lactating cows can increase daily milk production by 1.2kg (P<0.01), milk fat percentage by 0.3 percentage points, and milk protein content by 0.2%. At the same time, the rumen acetic acid/propionic acid ratio decreased from 3.2 to 2.8, promoting the conversion of energy to milk fat. According to data from the International Silage Federation (ISF), the aerobic stability of silage pretreated with brewing yeast was extended by 36 hours, and the content of butyric acid was reduced by 40%, significantly improving the palatability of the feed.
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2. Collaborative fattening and emission reduction of beef cattle

      According to a 2023 study in Animal Nutrition, adding 1% brewing yeast cell wall (10% oligosaccharides) to beef cattle feed can increase daily weight gain by 9.5% and feed conversion rate by 7.8% during the fattening period. Its cell wall polysaccharides reduce fecal nitrogen excretion by 22% by adsorbing rumen ammonia nitrogen, while in vitro simulation experiments show a decrease in methane production by 18% (compared to the control group), which is in line with the recommendations of the United Nations Food and Agriculture Organization (FAO) ruminant emission reduction technology guidelines.
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3、 Aquaculture: Immune enhanced and environmentally friendly aquaculture

1. Disease resistance and growth promotion in fish and shrimp

      In Southeast Asian shrimp farming, Aquaculture data from 2021 showed that adding 2% brewing yeast hydrolysate (small peptide content ≥ 35%) to feed can increase the survival rate of Vannamei shrimp by 17% (90 day farming cycle survival rate 82% vs control group 69%), and prolong the survival time by 48 hours after infection with white spot syndrome virus (WSSV). In the rainbow trout breeding experiment, adding 1.5% brewing yeast (containing 15% β - glucan) increased serum lysozyme activity by 31% and reduced the mortality rate of Aeromonas hydrophila infection by 35% (P<0.05).
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2. Water quality improvement and resource recycling

      According to the OECD2022 Environmental Report, the cell wall of brewing yeast can adsorb 85% of nitrite in water (decreasing to 0.75ppm within 24 hours at an initial concentration of 5ppm), and its secreted extracellular protease (≥ 500U/g) can degrade 60% of the protein in the residual feed, reducing the generation of ammonia nitrogen. According to the breeding data of Thailand's CP Group, the use of brewing yeast in the circulating water system reduces water change frequency by 40% and increases breeding density by 25%, which meets the ASME BPVC breeding engineering standards.
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4、 Poultry Farming: From Egg Production Performance to Immune Barrier Construction

1. High yield and quality improvement of laying hens

      A 2020 study by Poultry Science showed that adding 3% brewing yeast (containing 8% oligosaccharides) to the diet of laying hens can increase egg production by 6.8% (89% at 90 weeks of age compared to 83.3% in the control group), increase eggshell thickness by 4.2%, and increase Haff units by 7.5 units. Its rich vitamin B12 (≥ 200 μ g/kg) can reduce the incidence rate of fatty liver in laying hens by 30%, which conforms to the poultry nutrition standards of the American Association of Feed Management (AAFCO).
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2. Disease resistance and efficient breeding of broiler chickens

      The EU EFSA 2023 assessment report states that adding 1000ppm live brewing yeast cells to broiler diets can increase the bursa index by 15%, increase Newcastle disease antibody titers (HI) by 2 logarithmic orders of magnitude, and reduce feed to meat ratio by 5.6% (35 day old FCR 1.52 vs control group 1.61). The glutathione (≥ 100mg/kg) it contains can reduce serum cortisol levels by 28% under heat stress, significantly improving the welfare status of broiler chickens.
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5、 Quality Standards and Global Compliance

      The international quality control of feed grade brewing yeast follows the following standards:
Nutritional indicators: crude protein (AOAC 990.03) ≥ 45%, moisture (ISO 6496) ≤ 10%, ash content (AOAC 942.05) ≤ 8%

      Functional ingredients: β - glucan (Megazyme kit) ≥ 20%, oligosaccharides ≥ 8%, viable cell count (plate counting method) ≥ 1 × 10 ⁸ CFU/g (ruminant specific type)
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      Safety: Aflatoxin B1 (ELISA method) ≤ 5ppb, Salmonella (ISO 6579) cannot be detected
The US FDA, EU EC No 183/2005, and China GB 13078 all list it as a safe feed ingredient, allowing for unlimited addition in animal diets (except for ruminants, which need to control the wall breaking rate to be ≥ 90% to avoid cell wall residue).